Hedgehog signaling controls segmentation dynamics and diversity via msx1 in a spider embryo
نویسندگان
چکیده
منابع مشابه
Msx1 controls inductive signaling in mammalian tooth morphogenesis.
Members of the Msx homeobox family are thought to play important roles in inductive tissue interactions during vertebrate organogenesis, but their precise developmental function has been unclear. Mice deficient for Msx1 exhibit defects in craniofacial development and a failure of tooth morphogenesis, with an arrest in molar tooth development at the E13.5 bud stage. Because of its potential for ...
متن کاملS15-01 Cilia and Hedgehog signaling in the mouse embryo
The specification of cell types in the ventral half of the mouse neural tube depends on graded activity of the Sonic hedgehog (Shh) signaling pathway. Our genetic studies on neural patterning led to the surprising discovery that primary cilia are required for mammalian cells to transmit signals from the membrane protein Smoothened (Smo) to the Gli transcription factors. To understand why the pr...
متن کاملSeasonal dynamics of arboreal spider diversity in a temperate forest
Measuring and estimating biodiversity patterns is a fundamental task of the scientist working to support conservation and inform management decisions. Most biodiversity studies in temperate regions were often carried out over a very short period of time (e.g., a single season) and it is often-at least tacitly-assumed that these short-term findings are representative of long-term general pattern...
متن کاملTravelling and splitting of a wave of hedgehog expression involved in spider-head segmentation
During development segmentation is a process that generates a spatial periodic pattern. Peak splitting of waves of gene expression is a mathematically predicted, simple strategy accounting for this type of process, but it has not been well characterized biologically. Here we show temporally repeated splitting of gene expression into stripes that is associated with head axis growth in the spider...
متن کاملHoxb1 controls effectors of sonic hedgehog and Mash1 signaling pathways.
The diverse neuronal subtypes in the adult central nervous system arise from progenitor cells specified by the combined actions of anteroposterior (AP) and dorsoventral (DV) signaling molecules in the neural tube. Analyses of the expression and targeted disruption of the homeobox gene Hoxb1 demonstrate that it is essential for patterning progenitor cells along the entire DV axis of rhombomere 4...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Science Advances
سال: 2020
ISSN: 2375-2548
DOI: 10.1126/sciadv.aba7261